Compound class

Neurotrophic peptide mimetics

Small synthetic peptides designed to mimic regions of neurotrophic factors, typically characterised through downstream pathway readouts rather than a demonstrated direct receptor target.

Published: 2026-09-13Literature/identifier verification: 2026-09-13

Neutral class definition

Small synthetic peptides designed to mimic regions of neurotrophic factors, typically characterised through downstream pathway readouts rather than a demonstrated direct receptor target.

Related compounds

Compound

P021 (P21)

P021 is a small acetylated tetrapeptide carrying an adamantane-derived C-terminal extension, designed as a CNTF-derived peptide mimetic.

P21 · P-21 · Peptide 021

Related molecular mechanisms

No published mechanisms are currently linked to this category.

Relevant glossary terms

Agonist Ligand G-protein-coupled receptor Peptide analog Lipidation Amidation

Verified bibliography

Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice.
Li B, Wanka L, Blanchard J, Liu F, Chohan MO, Iqbal K, Grundke-Iqbal I
FEBS letters · 2010-06-30 · Journal Article
current
PMID 20600002 DOI 10.1016/j.febslet.2010.06.025 P021 (P21)