Selank 10mg
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) combining the tuftsin tetrapeptide (Thr-Lys-Pro-Arg) with the Pro-Gly-Pro (PGP) stabilizing sequence also used in Semax. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank is classified as an anxiolytic and nootropic peptide in Russian pharmacopoeia. It modulates GABAergic neurotransmission and has demonstrated anxiolytic-like effects comparable to benzodiazepines without sedation, motor impairment, or dependence potential in preclinical models. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
Select Option
2+ save 5% · 5+ save 10% · 10+ save 20%
- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Certificates published per tested lot — see current coverage
Mechanism of Action
Selank enhances GABA-A receptor sensitivity to GABA without direct benzodiazepine site binding, increasing GABAergic inhibitory tone in limbic structures. It also modulates serotonin metabolism by inhibiting enkephalinase activity, increasing endogenous enkephalin levels. Additionally, Selank upregulates IL-6 expression, modulates T-helper cell balance (Th1/Th2), and enhances NK cell activity, indicating immunomodulatory properties. The tuftsin component is a known phagocytosis-stimulating peptide recognized by neutrophils and macrophages.
Properties
CAS Number
129954-34-3
Molecular Formula
C₃₃H₅₇N₁₁O₉
Molecular Weight
751.87 Da
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Half-Life
~3-5 minutes (peripheral)
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- No third-party certificate has been published for this compound yet.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Certificates are published for each lot we have tested — see the 14 published so far.
Research Applications
References & Citations
(2)Anxiolytic action of the synthetic peptide Selank
Seredenin SB, Kozlovskii II, Blednov YA, et al.
Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia
Zozulia AA, Neznamov GG, Siuniakov TS, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.