Tesamorelin 10mg
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH 1-44) with a trans-3-hexenoic acid modification at the N-terminus that confers enhanced stability against DPP-IV enzymatic degradation. It stimulates endogenous pulsatile GH secretion from anterior pituitary somatotrophs, preserving the feedback regulation that exogenous GH bypasses. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
Strength
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2+ save 5% · 5+ save 10% · 10+ save 20%
- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Third-party tested — lot TSM-20260828-01 at 99.74% purity
Batch Tracking
Batch #
TSM-20260828-01
Tested
2026-09-08
Purity
99.74%
Method
RP-HPLC (214 nm)
Mechanism of Action
Tesamorelin binds the GHRH receptor (GHRH-R) on pituitary somatotrophs, activating Gs-coupled cAMP/PKA signaling that stimulates GH gene transcription, GH synthesis, and GH secretory granule exocytosis. Unlike exogenous GH, tesamorelin preserves the pulsatile GH secretion pattern and maintains feedback sensitivity to somatostatin and IGF-1. In research models this pulsatile GH release is studied for visceral-adipose lipolysis signaling without the supraphysiologic IGF-1 elevation associated with exogenous GH.
Properties
CAS Number
218949-48-5
Molecular Formula
C₂₂₁H₃₆₆N₇₂O₆₇S₁
Molecular Weight
5135.89 Da
Half-Life
~26-38 minutes
Storage
Store lyophilized at 2-8°C. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- Independently tested by Bioviridian Inc. — identity by LC-MS/MS, purity by RP-HPLC (214 nm).
- Measured at 99.74% purity on lot TSM-20260828-01.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Research Applications
References & Citations
(2)Metabolic effects of a growth hormone-releasing factor in patients with HIV
Falutz J, Allas S, Blot K, et al.
Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial
Stanley TL, Feldpausch MN, Oh J, et al.
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Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.