Molecular mechanism
CD36 scavenger receptor
A multifunctional scavenger receptor, distinct from the growth hormone secretagogue receptor, reported as a binding target for certain synthetic secretagogue peptides. It is recorded separately here precisely because collapsing it into the ghrelin-receptor mechanism would erase the finding that these compounds are not pharmacologically interchangeable.
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Neutral molecular overview
A multifunctional scavenger receptor, distinct from the growth hormone secretagogue receptor, reported as a binding target for certain synthetic secretagogue peptides. It is recorded separately here precisely because collapsing it into the ghrelin-receptor mechanism would erase the finding that these compounds are not pharmacologically interchangeable.
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Target identifiers
- Gene symbols
- CD36
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Related compounds
Compound
Examorelin (Hexarelin)
Examorelin, widely supplied as hexarelin, is a synthetic hexapeptide growth hormone secretagogue carrying a 2-methylated D-tryptophan.
Compound
Pralmorelin (GHRP-2)
Pralmorelin is a synthetic hexapeptide growth hormone secretagogue acting at the ghrelin receptor, containing three D-configured residues and a naphthylalanine substitution.
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Related mechanisms
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Verified bibliography
- CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart.current
Bodart V, Febbraio M, Demers A, McNicoll N, Pohankova P, Perreault A, Sejlitz T, Escher E, Silverstein RL, Lamontagne D, Ong H
Circulation research · 2002-05-03 · Journal Article
- Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study.current
Demers A, McNicoll N, Febbraio M, Servant M, Marleau S, Silverstein R, Ong H
The Biochemical journal · 2004-09-01 · Journal Article
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Related glossary terms
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Related Purely Peptides research articles
No existing Research Article is mapped to this mechanism seed record.